The Center For Disease Dynamics, Economics & Policy

Uncomplicated Urinary Tract Infection (UTI)

Clinical definition:

Infection of the bladder and lower urinary tract. Symptoms include urgency, dysuria, and frequency of micturition. UTIs are more common in women than men. Commonly caused by the enterobacteriales, E. coli and K. pneumoniae

 

Preferred antibiotic choice(s)
Drug Formulation Dosage Duration
Nitrofurantoin (PO) Oral liquid: 25 mg/5 mL; Tablet: 100 mg. 50 mg 6 hourly 5 days
Amoxicillin + clavulanic acid (PO) Oral liquid: 125 mg amoxicillin + 31.25 mg clavulanic acid/5 mL AND 250 mg amoxicillin + 62.5 mg clavulanic acid/5 mL;

Tablet: 500 mg (as trihydrate) + 125 mg (as potassium salt).

500 mg of amoxicillin component 12 hourly 5 days

Principles of Stewardship:

  • Treatment with quinolones should be avoided.
  • Do not treat patients with asymptomatic bacteriuria except in pregnancy and consider in those persons undergoing genitourinary tract biopsy.