The Center For Disease Dynamics, Economics & Policy

Mild to Moderate Acute Uncomplicated Prostatitis

Clinical definition:

Common symptoms include fever, chills, malaise, myalgia, pelvic pain, dysuria, and cloudy urine. In younger patients, common etiologies include N. gonorrheae and C. trachomatis. In older patients, common etiologies include Enterobacteriaceae species.


Preferred antibiotic choice(s)
Drug Formulation Dosage Duration
Ciprofloxacin (PO) Oral liquid: 250 mg/5 mL (anhydrous); Tablet: 250 mg (as hydrochloride) 500 mg 12 hourly 10 – 14 days
Alternative antibiotic choice(s)
Azithromycin Capsule: 250 mg; 500 mg (anhydrous); Oral liquid: 200 mg/5 mL 500 mg daily 3 days


  • In sexually active men, syndromic treatment for gonorrhoea and chlamydia should be added, as per national protocol.